Document Type



Cystic Fibrosis (CF) is a genetic disease of the exocrine gland (Gardner, 2007). The disease is characterized by thick secretion in organs (Lorenco, Costa and da Silva Filho, 2014). Chronic coughing can also be seen due to the thick secretions accumulating (Gardner, 2007). The transmembrane regulator gene is responsible for encoding an epithelial chloride channel (Lorenco, Costa and da Silva Filho, 2014).Thick viscous secretions through the respiratory tract and other organs, occur because the channel does not properly transport chloride and sodium to the epithelial membranes (Lorenco, Costa and da Silva Filho, 2014). The secretion in the respiratory system leads to decrease lung function (Lorenco, Costa and da Silva Filho, 2014). Many of the characteristics that are seen in CF are factors that affect voice, for example optimal respiration is required as a power source for phonation. Vocal fold thickness and the excessive mucus that covers them as a result of the disease are known to change vibratory patterns and voice abnormalities. Chronic coughing can also contribute to voice disorders (Gibson and Vertigan, 2009). This study utilizes the Voice-Handicap Index and the Voice-Related Quality of Life, as well as Qualtrics Survey Software to understand the perception of one’s voice in those living with Cystic fibrosis.


Communication Sciences and Disorders

Thesis Comittee

Suzanne Miller (Thesis Director)

Susan Gray

Ahmed Abdelal

Copyright and Permissions

Original document was submitted as an Honors Program requirement. Copyright is held by the author.